Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.941


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VDRhg19_v1_chr12_-_48298765_482988370.751.8e-14Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_226736603 6.120 C1orf95
chromosome 1 open reading frame 95
chr22_+_50624353 5.436 NM_025204
TRABD
TraB domain containing
chr17_-_39216343 5.031 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr22_+_50624267 4.890 TRABD
TraB domain containing
chr17_-_39222126 4.731 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr11_+_73087670 4.193 NM_032871
RELT
RELT tumor necrosis factor receptor
chr17_-_39211462 4.010 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr7_+_97841565 3.955 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr14_-_34419957 3.883 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr14_-_101034261 3.732 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr17_-_39203423 3.708 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr3_-_27764197 3.466 EOMES
eomesodermin
chr19_+_42259397 3.430 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr9_+_140125208 3.269 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr1_+_226736500 3.203 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr8_-_8239188 2.972 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr13_+_24844846 2.950 SPATA13
spermatogenesis associated 13
chr9_+_131644780 2.571 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr19_-_51472003 2.530 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr21_-_47575472 2.329 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr3_-_59035737 2.255 C3orf67
chromosome 3 open reading frame 67
chr10_-_33623771 2.209 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr11_-_111383063 2.177 NM_017589
BTG4
B-cell translocation gene 4
chr11_+_64126616 2.142 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr8_-_93115453 2.047 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr18_+_48086402 1.967 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr7_+_143078444 1.891 ZYX
zyxin
chr7_+_143078457 1.890 ZYX
zyxin
chr19_+_1941157 1.873 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr1_+_200993041 1.841


chr7_+_143078358 1.781 NM_001010972
NM_003461
ZYX

zyxin

chr2_+_108905094 1.732 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr11_+_1213469 1.680 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr1_+_175036993 1.670 NM_022093
TNN
tenascin N
chr1_+_47137496 1.645 NM_001145474
ATPAF1-AS1
ATPAF1 antisense RNA 1 (non-protein coding)
chr2_-_204399906 1.637 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr1_-_175712669 1.556 NM_003285
TNR
tenascin R (restrictin, janusin)
chr12_-_77459198 1.497 NM_203394
E2F7
E2F transcription factor 7
chr17_+_38498270 1.491 NM_001024809
RARA
retinoic acid receptor, alpha
chr7_+_39989603 1.445 CDK13
cyclin-dependent kinase 13
chr19_+_41620336 1.438 NM_000774
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr17_-_20370819 1.425 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr1_-_3816823 1.420 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr10_-_43892160 1.412 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr10_-_43892697 1.400 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr10_-_43892675 1.386 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr19_+_42817434 1.381 NM_173633
TMEM145
transmembrane protein 145
chr3_-_54961961 1.374 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr19_+_56186569 1.354 EPN1
epsin 1
chr19_+_1941184 1.321 CSNK1G2
casein kinase 1, gamma 2
chr1_-_203154304 1.320 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr10_-_33623978 1.316 NRP1
neuropilin 1
chr19_+_56186426 1.314 NM_001130072
NM_013333
EPN1

epsin 1

chr15_+_91428271 1.313 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr19_-_14260728 1.281 LPHN1
latrophilin 1
chr22_+_18593556 1.263 TUBA8
tubulin, alpha 8
chr7_+_39989871 1.260


chr5_-_72744351 1.258 NM_004472
FOXD1
forkhead box D1
chr19_-_51472816 1.257 NM_002774
KLK6
kallikrein-related peptidase 6
chr12_-_21548370 1.246 NM_134431
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr1_-_201342318 1.244 TNNT2
troponin T type 2 (cardiac)
chr12_-_109251333 1.238 NM_001161330
NM_018984
SSH1

slingshot homolog 1 (Drosophila)

chr1_-_203317366 1.235 FMOD
fibromodulin
chr16_-_89768094 1.203 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr1_+_26517051 1.151 NM_198137
CATSPER4
cation channel, sperm associated 4
chr16_-_4292052 1.143 NM_001098814
SRL
sarcalumenin
chr13_-_53313924 1.122 NM_001011705
NM_007015
LECT1

leukocyte cell derived chemotaxin 1

chr3_-_27763784 1.075 NM_005442
EOMES
eomesodermin
chr17_+_18380097 1.074 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr2_-_230786712 1.060 TRIP12
thyroid hormone receptor interactor 12
chr1_-_154474524 1.048 NM_001010846
SHE
Src homology 2 domain containing E
chr8_+_22437983 1.041 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr18_-_6414900 1.035 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr7_+_155089483 1.012 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr19_+_45394642 1.003 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr6_-_42016383 1.000 CCND3
cyclin D3
chr1_-_3816704 0.997 C1orf174
chromosome 1 open reading frame 174
chrX_-_138286434 0.995 FGF13
fibroblast growth factor 13
chr3_-_71114006 0.987 NM_001244813
FOXP1
forkhead box P1
chr1_-_205325915 0.979 NM_018203
KLHDC8A
kelch domain containing 8A
chr1_+_94057518 0.974 LOC100129046
uncharacterized LOC100129046
chr13_-_51417831 0.946 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr11_+_124609841 0.946 NRGN
neurogranin (protein kinase C substrate, RC3)
chr16_+_6823809 0.944 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_122339186 0.939 NM_139175
RNF133
ring finger protein 133
chr19_-_42759279 0.921 NM_006494
ERF
Ets2 repressor factor
chr10_+_11047339 0.918 CELF2
CUGBP, Elav-like family member 2
chr1_-_154943001 0.912 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr11_-_66084501 0.904 NM_020404
CD248
CD248 molecule, endosialin
chr19_+_12175513 0.898 NM_001136501
ZNF844
zinc finger protein 844
chr19_+_56186580 0.895 EPN1
epsin 1
chr7_+_155089614 0.892 INSIG1
insulin induced gene 1
chr13_-_53313835 0.886 LECT1
leukocyte cell derived chemotaxin 1
chr6_-_88038995 0.876 NM_198568
GJB7
gap junction protein, beta 7, 25kDa
chr2_-_217560247 0.874 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_-_153585504 0.874 NM_080388
S100A16
S100 calcium binding protein A16
chr9_+_79634570 0.868 NM_001013735
FOXB2
forkhead box B2
chrX_+_106161589 0.862 NM_001171095
CLDN2
claudin 2
chr13_+_114321469 0.858 NM_002929
GRK1
G protein-coupled receptor kinase 1
chr1_-_40157067 0.847 NM_016257
HPCAL4
hippocalcin like 4
chr21_+_45875368 0.813 NM_030891
LRRC3
leucine rich repeat containing 3
chr11_-_124805896 0.809 HEPACAM
hepatic and glial cell adhesion molecule
chrX_+_52928408 0.804 NM_001099684
FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chr6_-_42016609 0.799 NM_001136017
NM_001136126
CCND3

cyclin D3

chr14_-_101351183 0.796 NM_001134888
RTL1
retrotransposon-like 1
chr13_+_50760015 0.791


chr19_-_47987475 0.790 NM_007059
KPTN
kaptin (actin binding protein)
chr19_+_49607925 0.787 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr11_-_124806302 0.786 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr19_+_13250072 0.777 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr8_+_86157693 0.773 NM_198584
CA13
carbonic anhydrase XIII
chr2_-_230786618 0.772 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr7_-_44365019 0.763 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr13_+_51796363 0.758 NM_001242312
NM_145019
FAM124A

family with sequence similarity 124A

chr11_+_76883823 0.755 MYO7A
myosin VIIA
chr2_+_85921413 0.753 NM_006433
NM_012483
GNLY

granulysin

chr1_-_201081693 0.750 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_+_20646831 0.744 NM_004040
RHOB
ras homolog gene family, member B
chr16_+_56623266 0.741 NM_005954
MT3
metallothionein 3
chr20_-_52790511 0.734 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr10_+_11047253 0.726 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr6_+_151646634 0.726 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_60869929 0.721 NM_014207
CD5
CD5 molecule
chr6_-_31080331 0.708 NM_014070
C6orf15
chromosome 6 open reading frame 15
chr3_+_184032414 0.707 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_38273823 0.690 YRDC
yrdC domain containing (E. coli)
chr15_-_65398578 0.688 NM_001163692
UBAP1L
ubiquitin associated protein 1-like
chr8_+_76320106 0.681 HNF4G
hepatocyte nuclear factor 4, gamma
chr3_+_51741080 0.681 NM_000839
NM_001130063
GRM2

glutamate receptor, metabotropic 2

chr22_-_31536339 0.671 NM_015715
PLA2G3
phospholipase A2, group III
chr8_+_99956630 0.670 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr14_+_50359816 0.664 ARF6
ADP-ribosylation factor 6
chr3_+_48264836 0.660 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr12_+_119772516 0.660 NM_178499
CCDC60
coiled-coil domain containing 60
chr7_+_91763851 0.654 LOC613126
uncharacterized LOC613126
chr16_+_28889808 0.653 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr1_-_41487386 0.648 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr5_-_141993691 0.642 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chrX_+_119495939 0.642 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr19_+_38042275 0.641 NM_152606
LOC100507433
ZNF540
uncharacterized LOC100507433
zinc finger protein 540
chr11_-_64527369 0.631 PYGM
phosphorylase, glycogen, muscle
chr19_-_47987410 0.631 KPTN
kaptin (actin binding protein)
chr1_+_156549518 0.626 NM_001105669
TTC24
tetratricopeptide repeat domain 24
chr19_+_7985193 0.624 NM_003083
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr19_+_56186610 0.623 EPN1
epsin 1
chrX_-_130423034 0.622 NM_001170963
IGSF1
immunoglobulin superfamily, member 1
chr20_+_42875905 0.618 NM_024034
GDAP1L1
ganglioside-induced differentiation-associated protein 1-like 1
chr19_+_1383877 0.612 NM_024407
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr7_+_143078395 0.611 ZYX
zyxin
chr3_+_184032243 0.607 NM_001194946
NM_001194947
NM_198241
NM_198242
NM_198244
EIF4G1




eukaryotic translation initiation factor 4 gamma, 1




chr22_+_31489343 0.606 SMTN
smoothelin
chrX_-_48776282 0.603 NM_006875
PIM2
pim-2 oncogene
chr11_+_57228126 0.600 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr1_-_228463727 0.597


chr1_-_155939051 0.591 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_25264913 0.589 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr19_-_42759151 0.584 ERF
Ets2 repressor factor
chr20_+_42875943 0.577 GDAP1L1
ganglioside-induced differentiation-associated protein 1-like 1
chr19_+_10791025 0.575


chr1_+_20465818 0.569 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr5_-_179051586 0.565 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr6_-_31846766 0.556 SLC44A4
solute carrier family 44, member 4
chr1_+_35258598 0.554 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr16_-_4466607 0.539 CORO7
coronin 7
chr19_-_2783313 0.538 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr2_+_233498206 0.538 NM_025202
EFHD1
EF-hand domain family, member D1
chr1_+_109234908 0.538 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr9_-_136603444 0.532 NM_001134707
SARDH
sarcosine dehydrogenase
chr21_+_25801042 0.526 FLJ42200
FLJ42200 protein
chr3_+_184032319 0.525 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_+_19322763 0.524 NM_004386
NCAN
neurocan
chr19_+_39936240 0.522 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr17_+_75447325 0.513 SEPT9
septin 9
chr19_+_39936275 0.513 NM_003169
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr22_-_30867944 0.512 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr7_+_150446823 0.507 NM_001162367
LOC100128542
uncharacterized LOC100128542
chr19_+_1383904 0.507 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr11_+_76839309 0.498 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr21_-_44299660 0.495 NM_018669
NM_033661
WDR4

WD repeat domain 4

chr19_+_1383898 0.493 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr22_+_45705965 0.491 FAM118A
family with sequence similarity 118, member A
chr21_-_44299605 0.487 WDR4
WD repeat domain 4
chr1_+_154474694 0.486 NM_001098475
NM_182499
TDRD10

tudor domain containing 10

chr1_+_209757044 0.485 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr6_+_7107799 0.484 NM_001168344
RREB1
ras responsive element binding protein 1
chr17_-_72855884 0.483 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_+_39574944 0.480 NM_001004318
PAPL
iron/zinc purple acid phosphatase-like protein
chr17_+_65373362 0.477 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr20_+_42193754 0.474 NM_001199264
SGK2
serum/glucocorticoid regulated kinase 2
chr22_+_45705766 0.467 NM_017911
FAM118A
family with sequence similarity 118, member A
chr16_+_31119730 0.464 BCKDK
branched chain ketoacid dehydrogenase kinase
chr16_-_4466520 0.462 CORO7
coronin 7
chr18_+_77623667 0.462 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr16_-_3767449 0.462 NM_016292
TRAP1
TNF receptor-associated protein 1
chr5_-_32174355 0.461 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr7_-_148787866 0.459 NM_152411
ZNF786
zinc finger protein 786
chr9_+_139249251 0.458 NM_001200003
GPSM1
G-protein signaling modulator 1
chr7_+_39989955 0.456 NM_003718
NM_031267
CDK13

cyclin-dependent kinase 13

chr19_+_39936251 0.456 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr1_-_155947898 0.453 NM_004723
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.